abstract：:Proliferative lesions, which include collagen, elastic fibers and abnormally oriented muscle fibers, were found to develop in intramyocardial arteries more rapidly with age in cigarette smokers than in nonsmokers. The study attempted to determine whether these lesions reduce perfusion pressures in the subendocardial z...

journal_title：American journal of clinical pathology

authors： Naeye RL,Truong LD

更新日期：1977-10-01 00:00:00

abstract：:Possible increased activation of the coagulation pathway was measured in a group of patients with neoplastic diseases. In addition to standard tests, the thromboplastin generation test, thrombin generation test and immunologic and coagulant activities of both Factor VIII and antithrombin III were utilized in the evalu...

journal_title：American journal of clinical pathology

authors： Losito R,Beaudry P,Valderrama JC,Cousineau L,Longpré B

更新日期：1977-08-01 00:00:00

abstract：:The present report is that of a civilian episode of fatal, fulminant group Y meningococcemia in a previously healthy adolescent, who denied prior vaccination against group C meningococcus. The patient suffered abrupt onset of purpura, hypotension and cardiopulmonary arrest. A detailed clinical and pathologic report is...

journal_title：American journal of clinical pathology

authors： Bernad PG,Snyder DA,Levey M

更新日期：1977-08-01 00:00:00

abstract：:Counterimmunoelectrophoresis was used to detect Cryptococcus neoformans capsular polysaccharide in the body fluids of infected patients. Using rabbit anti-C. neoformans A15 globulin, counterimmunoelectrophoresis detected 1.25 microgram of purified cryptococcal polysaccharide per ml of cerebrospinal fluid (CSF) or urin...

journal_title：American journal of clinical pathology

authors： Maccani JE

更新日期：1977-07-01 00:00:00

abstract：:The incubation of stored blood in a mixture of inosine, pyruvate, glucose, and phosphate restores the O2 affinity of hemoglobin to physiologic levels, as measured by the configuration of the dissociation curve and the P50. This regeneration of normal hemoglobin function not only is consistent for samples anticoagulate...

journal_title：American journal of clinical pathology

authors： Sumoza A,Fairbanks VF,Pineda AA

更新日期：1977-07-01 00:00:00

abstract：:Forty-three laboratories participated in an interlaboratory testing program offered by the College of American Pathologists for the radioimmunoassay (RIA) of carcinoembryonic antigen (CEA). Thirty correctly reported a sample with 1.9 ng of endogenous CEA per ml as less than 2.5 ng. For samples with added exogenous CEA...

journal_title：American journal of clinical pathology

authors： Reynoso G,Keane M,Konopka S

更新日期：1977-07-01 00:00:00

abstract：:This report concerns a particular benign histologic variant of Hodgkin's disease, the lymphocyte-predominant category of the Rye classification. The group of 24 cases, all involving localized disease, was first reported in 1960, and is now reappraised, incorporating subsequent data. The interpretations of the original...

journal_title：American journal of clinical pathology

authors： Wright CJ

更新日期：1977-06-01 00:00:00

abstract：:Two hundred forty-three patients who had pathologically verified primary osteosarcomas of bone, treated at The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute over a 24-year period, form the basis of this study. These cases provide a basis for comparison of those patients currentl...

journal_title：American journal of clinical pathology

authors： Uribe-Botero G,Russell WO,Sutow WW,Martin RG

更新日期：1977-05-01 00:00:00

abstract：:Specific esterase activity, a property generally ascribed to cells of granulocytic origin, was found in abnormal erythroid precursors obtained from the bone marrows of six patients with untreated erythroleukemia. These erythroblasts also showed nonspecific esterase activity. Neither specific nor nonspecific esterase a...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1977-04-01 00:00:00

abstract：:Suspensions of lymphoid cells from tissues have been used for the determination of the quantitative relationship between the T and B cell populations. The distribution of the lymphocytes within a given tissue, however, cannot be demonstrated once such a suspension has been prepared. Various methods of characterizing l...

journal_title：American journal of clinical pathology

authors： Millard PR,Rabin BS,Whiteside TL,Hubbard JD

更新日期：1977-03-01 00:00:00

abstract：:A survey of adult patients admitted to a general hospital showed that 1.5% had hepatitis B surface antigen in the blood and 22% had hepatitis antibody. The majority of patients with hepatitis B did not have clinical hepatitis and would not have been recognized without screening all hospital admissions for hepatitis B ...

journal_title：American journal of clinical pathology

authors： Linnemann CC Jr,Hegg ME,Ramundo N,Schiff GM

更新日期：1977-03-01 00:00:00

abstract：:The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...

journal_title：American journal of clinical pathology

authors： Nussbaum B,Minckler T,Roby R,Ackerman E

更新日期：1977-02-01 00:00:00

abstract：:Postmortem pathologic and bacteriologic reports were analyzed for 237 deaths occurring at a large institution for the mentally retarded from 1958 to 1973. Bronchopneumonia, aspiration pneumonia, and lipid pneumonia were frequently reported at autopsy, and in a total of 146 cases (61.6%) at least one type of pneumonia ...

journal_title：American journal of clinical pathology

authors： Polednak AP

更新日期：1977-02-01 00:00:00

abstract：:A two-sample plot is often used to display test results in clinical chemistry external quality control programs. The use of control materials at different concentrations calls for a re-evaluation of the two-sample plot. A modification of the two-sample plot is presented. The axes of the graph are graduated in units of...

journal_title：American journal of clinical pathology

authors： Elion-Gerritzen WE

更新日期：1977-01-01 00:00:00

abstract：:In a child with renal failure and oliguria due to hyperoxaluria myelophthisis developed as a result of extensive bone-marrow replacement with calcium oxalate crystals and an accompanying fibrous proliferations. The histopathology associated with this metabolic disorder was demonstrated in posterior iliac crest bone-ma...

journal_title：American journal of clinical pathology

authors： McKenna RW,Dehner LP

更新日期：1976-12-01 00:00:00

abstract：:Several laboratory methods are currently available for the detection of barbiturates, but few are suitable for emergency use, The authors evaluated use of an ultraviolet spectrophotometric method as a screening procedure and compared the results with results obtained by other barbiturate methods (colorimetric, gas-li...

journal_title：American journal of clinical pathology

authors： Schumann GB,Lauenstein K,LeFever D,Henry JB

更新日期：1976-11-01 00:00:00

abstract：:The serum concentrations of alpha-fetoprotein of rats following experimental galactosamine-induced liver-cell necrosis accurately reflect the severity of preceding liver-cell damage as determined by elevation of serum transaminases. There is a very close correlation between the highest SGOT or SGPT serum activity foun...

journal_title：American journal of clinical pathology

authors： Sell S,Stillman D,Gochman N

更新日期：1976-11-01 00:00:00

abstract：:Histologic findings in liver biopsy specimens obtained from 88 patients before and one and two years after end-to-end jejunoileal bypass are compared. In addition to the expected fatty changes, mild changes of centrilobular, pericellular fibrosis were present in the initial biopsies in 8.6%; a year later they had beco...

journal_title：American journal of clinical pathology

authors： Marubbio AT Jr,Buchwald H,Schwartz MZ,Varco R

更新日期：1976-10-01 00:00:00

abstract：:Uterine tumors with histologic resemblances to ovarian sex-cord tumors were encountered in 14 women in the fourth to sixth decades of life, most of whom had abnormal vaginal bleeding and enlarged uteri suggesting leiomyomas. The tumors in six cases (Group I) were identical to one or another form of well-recognized end...

journal_title：American journal of clinical pathology

authors： Clement PB,Scully RE

更新日期：1976-09-01 00:00:00

abstract：:The cases of 20 patients, each of whom has a positive lupus erythematosus cell preparation and a negative antinuclear factor test, are presented. The concept of a false-positive lupus erythematosus preparation is suggested. Five common mechanisms causing a false-negative antinuclear factor test are discussed and evalu...

journal_title：American journal of clinical pathology

authors： Koller SR,Johnston CL Jr,Moncure CW

更新日期：1976-09-01 00:00:00

abstract：:A column chromatographic method for the simultaneous single-eluate isolation of CPK-MB and LDH 1,2 has been evaluated. The method is rapid in that the entire isolation is completed in less than an hour and subsequent analysis can be performed using presently available spectrophotometric methods and reagents without th...

journal_title：American journal of clinical pathology

authors： Lederer WH,Gerstbrein HL,McClintock WC

更新日期：1976-08-01 00:00:00

abstract：:The most common differentiated renal tumor of early childhood is the congenital mesoblastic neophroma. Well-differentiated forms of Wilms' tumor may present a difficult differential diagnosis from these benign neoplasms. The cases of two patients found to have well-differentiated renal neoplasms after being treated fo...

journal_title：American journal of clinical pathology

authors： Hughson MD,Hennigar GR,Othersen HB Jr

更新日期：1976-08-01 00:00:00

abstract：:Quantitative measurements of constituent concentrations of Survey specimens are generally recorded to the nearest integer or to the nearest tenth. Questions have arisen as to whether this degree of rounding of measurements is appropriate when available laboratory equipment can determine results more precisely. Statist...

journal_title：American journal of clinical pathology

authors： Williams GW,Schork MA

更新日期：1976-07-01 00:00:00

abstract：:Experiences of the CAP Survey Program in reticulocyte counts and morphologic identification of reticulocytes from 1971 to 1974 are reviewed. Problems of morphologic identification are reflected in an excessive variance of reticulocyte counts. Statistical sources of variations in counting are identified. The older, ori...

journal_title：American journal of clinical pathology

authors： Gilmer PR Jr,Koepke JA

更新日期：1976-07-01 00:00:00

abstract：:A case of congenital Pelger-Hüet anomaly of the peripheral blood cells is described. Electronmicroscopic examination of the blood cells revealed nuclear bridges and appendices in the polymorphonuclear leukocytes. The number of cytoplasmic granules was diminished, but the size of the secondary granules was markedly inc...

journal_title：American journal of clinical pathology

authors： Djaldetti M,Weiss S,Gafter U

更新日期：1976-06-01 00:00:00

abstract：:Three anti-Factor-VIII antibodies from hemophiliacs were reacted with samples of batches of Maws commerical bovine and porcine Factor VIII concentrates manufactured over a 12-year period. The apparent antibody concentrations varied widely with the different batches of concentrates. The variations are probably due to i...

journal_title：American journal of clinical pathology

authors： Edson JR,Swinehart CD

更新日期：1976-06-01 00:00:00

abstract：:The ability to inhibit the release reaction was found to correlate well with the ability to inhibit aggregation in washed human platelets exposed to antilymphocyte serum (ALS). However, the primary mechanism that contributes to ALS-induced aggregation in unwashed platelets appeared to be different from that found in w...

journal_title：American journal of clinical pathology

authors： Wang TY,Hussey CV,Hause LL,Fobian JE

更新日期：1976-05-01 00:00:00

abstract：:Several technics are currently being used to detect hepatitis type A antigen or its antibody. These include immunoelectronmicroscopy, immune adherence, and complement fixation. This paper describes another promising technic, a microtiter solid-phase immunoradiometric assay, in which hepatitis A antigen and antibody ar...

journal_title：American journal of clinical pathology

authors： Hollinger FB,Bradley DW,Dreesman GR,Melnick JL

更新日期：1976-05-01 00:00:00

abstract：:Cellular and humoral immunity combine to determine the outcome following exposure to hepatitis virus and are implicated in the proposed pathogenetic mechanism for acute and chronic hepatitis. Although antibody to HBsAg is found in virtually all following recovery from hepatitis B, a cell-mediated response to HBsAg can...

journal_title：American journal of clinical pathology

authors： Lee WM

更新日期：1976-05-01 00:00:00

abstract：:The levels of thymus-derived lymphocytes (T-cells) in samples of peripheral blood from 47 patients with carcinoma of the breast, 36 patients with benign mammary lesions, and 33 matched normal controls were determined. Results were analyzed with three statistical tests. It was found that the mean percentages of T-lymph...

journal_title：American journal of clinical pathology

authors： Keller SE,Ioachim HL,Pearse T,Siletti DM

更新日期：1976-04-01 00:00:00

abstract：:Utilizing a bacterial-agar overlay technic incorporating the methionine-requiring bacterium Leukonostoc mesenteroides, little or no bacterial growth was seen surrounding the megaloblasts and proerythroblasts of eight patients who had severe untreated pernicious anemia. Similarly, scant bacterial growth was observed in...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1976-04-01 00:00:00

abstract：:Cytogenetic studies of bone marrow were performed in 230 consecutive cases of patients with chronic granulocytic leukemia (CGL) admitted to the National Cancer Institute since 1961. Twenty patients lacked the Philadelphia (Ph1) chromosome. All were previously untreated. When compared with Ph1-positive patients, CGL pa...

journal_title：American journal of clinical pathology

authors： Canellos GP,Whang-Peng J,DeVita VT

更新日期：1976-04-01 00:00:00

abstract：:A fatal case of an apparently congenital form of hemophagocytic reticulosis is reported. The onset was manifested by hyperbilirubinemia and hepatosplenomegaly which were present at birth and persisted throughout life. Fever, anemia and pancytopenia developed at 1 month of age and became progressively worse. A splenect...

journal_title：American journal of clinical pathology

authors： Koto A,Morecki R,Santorineou M

更新日期：1976-04-01 00:00:00

abstract：:An antithrombin assay (AA) and an antithrombin assay modified by the addition of heparin (H-AA) were performed using sera from healthy subjects, patients predisposed to thrombosis, and patients with thromboembolic disease. Characteristic AA, and H-AA patterns were found in each group. Normal controls and four of 39 "p...

journal_title：American journal of clinical pathology

authors： Innerfield I,Stone ML,Mersheimer W,Clauss RD,Greenberg J

更新日期：1976-03-01 00:00:00

abstract：:Two cases of giant-cell arteritis of uterus were found incidentally in association with uterine prolapse. One similar case has been reported in the literature. Microscopic examination disclosed fragmentation of the elastic laminae of the myometrial arteries with a giant-cell and mononuclear infiltrate. The relationshi...

journal_title：American journal of clinical pathology

authors： Pirozynski WJ

更新日期：1976-03-01 00:00:00

abstract：:The presence of small gas bubbles in devices used to collect blood gas samples is considered. A gas bubble whose relative volume is 0.5 to 1% or more that of the liquid in the collection device is a potential source of significant error. Relationships describing the possible magnitude of this error are derived and sub...

journal_title：American journal of clinical pathology

authors： Mueller RG,Lang GE,Beam JM

更新日期：1976-02-01 00:00:00

abstract：:The development and general concepts of the Système International d'Unités (SI units) are discussed. The basic and derived quantities and units of the SI used for clinical laboratory data are reviewed. Ranges of normal values for a number of body fluid constituents are given in the units in current general use and in ...

journal_title：American journal of clinical pathology

authors： Lehmann HP

更新日期：1976-01-01 00:00:00

abstract：:The morphologic appearances of regional lymph nodes in radical mastectomy specimens obtained from 303 women entered into a prospective study of invasive breast cancer were categorized into patterns that have been considered to reflect immunologic function. An attempt was made to correlate these with 31 other histologi...

journal_title：American journal of clinical pathology

authors： Fisher ER,Gregorio R,Redmond C,Dekker A,Fisher B

更新日期：1976-01-01 00:00:00

abstract：:A case of unilateral gonadoblastoma in association with a ruptured ectopic tubal pregnancy is presented. The patient had normal menstrual history prior to a missed period followed by abdominal pain and the passage of clots. The surgical specimens, in addition to the ruptured tubal pregnancy, showed nodular foci of typ...

journal_title：American journal of clinical pathology

authors： Pratt-Thomas HR,Cooper JM

更新日期：1976-01-01 00:00:00

abstract：:Anemia developing during the course of chronic renal disease is a frequent complication often necessitating periodic transfusion therapy. A number of etiologic factors have been implicated, including decreased production of erythropoietin; decreased erythrocyte life span secondary to uremia and splenomegaly; increased...

journal_title：American journal of clinical pathology

authors： Hancock DE,Onstad JW,Wolf PL

更新日期：1976-01-01 00:00:00